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Effect of sex differences in remifentanil requirements for inhibiting cardiovascular response to CO2 pneumoperitoneum stimulus during propofol anesthesia

Effect of sex differences in remifentanil requirements for inhibiting cardiovascular response to CO2 pneumoperitoneum stimulus during propofol anesthesia

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-17011906
Enrollment
Unknown
Registered
2017-07-08
Start date
2017-07-10
Completion date
Unknown
Last updated
2017-07-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Laparoscopic surgery

Interventions

Male group:propofol and remifentanil
Female group:propofol and remifentanil

Sponsors

Anhui Provincial Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Patients scheduled for elective laparoscopic surgery; 2. Aged 20-60 years; 3. BMI 18-30 kg/m2; 4. ASA physical status I-II.

Exclusion criteria

Exclusion criteria: 1. History of cardiac, pulmonary, liver or renal disease; 2. Drug or alcohol abuse; 3. Current use of any vasoactive medications; 4. Recent use of any medications known to affect sympathetic adrenergic response

Design outcomes

Primary

MeasureTime frame
Median effective effect-site concentration of remifentanil inhibiting cardiovascular response to CO2 pneumoperitoneum stimulus when combined with propofol in patients undergoing laparoscopic surgery;—

Secondary

MeasureTime frame
Mean arterial pressure;Heart rate;BIS;—

Countries

China

Contacts

Public ContactLi Juan

Anhui Provincial Hospital

huamuzi1999@126.com+86 13956005465

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 28, 2026