choledocholithiasis
Conditions
Interventions
The group of successful operation (The control group):No intervention
The group of successful operation (The experimental group):Ursodeoxycholic acid will be administered at the dose of 13-15mg/kg for 1-2 times every day , and the treatment time more than 6 months
The group of stent implantation after the failed operation (The experimental group):Ursodeoxycholic acid will be administered at the dose of 13-15mg/kg for 1-2 times every day, and the treatment time
The group of stent implantation after the failed operation (The control group):No intervention
Sponsors
Department of Gastroenterology, The First Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients who were diagnosed as choledocholithiasis with preoperative imaging, confirmed by ERCP and treated voluntarily with ursodeoxycholic acid were enrolled in this study.
Exclusion criteria
Exclusion criteria: 1. Patients under 18 years old or without autonomy; 2. Patients for whom ERCP was not suitable. 3. Patients accompanied by basic diseases associated with heart ,lung and liver. 4. Patients with malignant tumors; 5. Patients who have undergone surgery(if they would be willing to join the latter follow- up, they could bedivided into a sigle group); 6. Patients who were pregnant or during breast feeding period; 7. Patients known to suffer from side effects associated with ursodeoxycholic acid or had been treated with ursodeoxycholic acid regularly.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| bilirubin;Total bile acid;phospholipid;Lecithin;Bile salt;Cholesterol; | — |
Secondary
| Measure | Time frame |
|---|---|
| calcium ion;ß-glucosidas; | — |
Countries
China
Contacts
Public ContactXu Jianming
Department of Gastroenterology, The First Affiliated Hospital of Anhui Medical University
Outcome results
None listed