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Multicenter randomized controlled study of ursodeoxycholic acid on biliary components and biliary plastic stent permeability

Multicenter randomized controlled study of ursodeoxycholic acid on biliary components and biliary plastic stent permeability

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-17011782
Enrollment
Unknown
Registered
2017-06-28
Start date
2017-06-01
Completion date
Unknown
Last updated
2017-07-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

biliary stricture

Interventions

Ursodeoxycholic acid:Ursodeoxycholic acid 13-15mg/kg, 1-2 times daily, treatment time is given for more than12 moths
The control group:Do not give anything

Sponsors

Department of Gastroenterology, The First Affiliated Hospital of Anhui Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients who were diagnosed as common biliary stricture with preoperative imaging and should undergo long-term biliary drainage, and were treated with ERCP placing a plastic stent or plastic stents, and were treated voluntarily with ursodeoxycholic acid were enrolled in this study.

Exclusion criteria

Exclusion criteria: 1. Patients under 18 years old or without autonomy; 2. Patients for whom ERCP were not suitable. 3. Patients accompanied by basic diseases associated with heart, lung and liver. 4. patients with malignant tumors, except for biliary tumors; 5. patients who have been treated with PTCD; 6. pregnant or lactating patients; 7. Patients known to suffer from side effects associated with ursodeoxycholic acid or had been treated with ursodeoxycholic acid regularly.

Design outcomes

Primary

MeasureTime frame
bilirubin;Total bile acid;phospholipid;Lecithin;Bile salt;Cholesterol;

Secondary

MeasureTime frame
calcium ion;ß-glucosidas;

Countries

China

Contacts

Public ContactXu Jianming

Department of Gastroenterology, The First Affiliated Hospital of Anhui Medical University

xujm1017@163.com+86 13955157272

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026