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Link between Pruritus and Poor Sleep Quality with Abnormal Epidermal Function in Childhood Atopic Dermatitis

Link between Pruritus and Poor Sleep Quality with Abnormal Epidermal Function in Childhood Atopic Dermatitis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-17011779
Enrollment
Unknown
Registered
2017-06-28
Start date
2017-06-01
Completion date
Unknown
Last updated
2017-07-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atopic Dermatitis

Interventions

AD treated with topical product:Topical use of Atopalm cream
AD with no treatment:no treatment
Healthy control:no treatment

Sponsors

Beijing Children’s Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) Comply with Williams diagnostic criteria of AD; (2) Mild AD of children with SCORAD score of <25; (2) The age of AD children is 6-18 years old, the men and women is not restricted; (3) Study before 1 weeks of treatment with AD, not too topical moisturizing agent, glucocorticoid, and oral antihistamines etc.

Exclusion criteria

Exclusion criteria: (1) The patient who doesn't meet the Williams diagnostic criteria for atopic dermatitis; (2) The patient who was acute attack with erosion, effusion and secondary infection; (3) The patient who are participating in other clinical studies or have participated in other clinical studies within 3 months; (4) The patient with severe immune hypofunction; (5) The patient with serious heart, liver and kidney diseases; (6) The patient with other skin diseases except atopic dermatitis are needed in the treatment area.

Design outcomes

Primary

MeasureTime frame
Epidermal Functions (Transepidermal water loss rates: TEWL, Stratum corneum hydration, Skin surface pH);

Secondary

MeasureTime frame
Sleep Quality;Pruritus Severity;Disease Severity;

Countries

China

Contacts

Public ContactLin MA

National Center for Children's Health China,Beijing Children’s Hospital, Capital Medical University

bch_maleen@aliyun.com+86 010-59616882

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026