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Effects of nimodipine on postoperative delirium in elderly under general anesthesia

Effects of nimodipine on postoperative delirium in elderly under general anesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-17011776
Enrollment
Unknown
Registered
2017-06-28
Start date
2017-08-01
Completion date
Unknown
Last updated
2017-07-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

prolapse of lumbar intervertebral disc

Interventions

Control group:standard treatment
Nimodipine group:pretreatment of nimodipine

Sponsors

the Third Hospital of Hebei Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Elderly patients with prolapse of lumbar intervertebral disc receiving posterior lumbar decompression bone grafting internal fixation under general anesthesia; 2. no history of traumatic brain injury, neurological diseases and alchol abuse; 3. no severe vision or hearing impairment and no obvious abnormality of heart, lung, liver and kidney function.

Exclusion criteria

Exclusion criteria: (1) operation time is longer than 3 hours; (2) The intraoperative blood loss is more than 800 ml; (3) operation was cancelled by various reasons

Design outcomes

Primary

MeasureTime frame
cognitive function;S100ß;glial fibrillary acidic protein;—

Countries

China

Contacts

Public ContactQiujun Wang

the Third Hospital of Hebei Medical University

13933178001@163.com+86 18533112929

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026