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Effect of methylprednisolone on inflammatory response after autotransfusion

Effect of methylprednisolone on inflammatory response after autotransfusion

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-17011736
Enrollment
Unknown
Registered
2017-06-21
Start date
2017-09-08
Completion date
Unknown
Last updated
2017-07-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lumbar laminectomy

Interventions

group M:500mg methylprednisolone(dissolved in 100ml saline) will be intravenous infused after anesthesia induction,with the infusion rate of 5ml / min
group C:infusion of the same volum of salin

Sponsors

Dept. of Anesthesiology,The Affliliated Hospital Of Xuzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 75 Years

Inclusion criteria

Inclusion criteria: Patients undergoing elective lumbar laminectomy, aged 30-75 years old, body mass index 18-23kg/m2, ASA I~II level, signed informed consent.

Exclusion criteria

Exclusion criteria: Liver and kidney dysfunction, heart failure, uncontrolled high blood pressure (no regular medication, systolic blood pressure control over 160mmHg), endocrine disease, electrolyte imbalance,immune system disease,allogeneic blood was transfused within 3 months.

Design outcomes

Primary

MeasureTime frame
white blood cell;TNF-a;IL-1ß;IL-6;IL-8;

Secondary

MeasureTime frame
length of hospital stay;

Countries

China

Contacts

Public ContactShuai Miao

Affiliated Hospital of Xuzhou Medical University

843916335@qq.com+86 18752113527

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026