Critical illness
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) adult patients admitted to intensive care units (=18 years old); 2) expected length of ICU stay more than 72 hours; 3) signed the informed consent.
Exclusion criteria
Exclusion criteria: 1) ICU readmission; 2) enrollment in another intervention study; 3) expected death within 24 hours; 4) donors for organ transplantation; 5) pregnant women; 6) only receive life-sustaining treatment; 7) indication of hyperbaric oxygenation: carbon monoxide intoxication, gas embolism, necrotizing fasciitis; 8) patients who need a different protocol for oxygen supplementation, such as patients with acute decompensation of chronic obstructive pulmonary disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 28 days mortality of first ICU admission; | — |
Secondary
| Measure | Time frame |
|---|---|
| the incidence of organ dysfunction in ICU;arterial blood lactate level;the incidence of infection in ICU;ventilator supporting time;the incidence of arrhythmia;mortality in ICU;90 days mortality of first ICU admission; | — |
Countries
China
Contacts
The affiliated hospital of Guizhou medical university