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Randomized Study of Clinical Effect of Nutrition Support During Chemoradiotherapy in Patients with Gastrointestinal Malignancies.

Randomized Study of Clinical Effect of Nutrition Support During Chemoradiotherapy in Patients with Gastrointestinal Malignancies.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-17011611
Enrollment
Unknown
Registered
2017-06-09
Start date
2017-07-01
Completion date
Unknown
Last updated
2017-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Digestive tract carcinoma (esophageal carcinoma, gasrtic carcinoma,carcinoma of large intestine)

Interventions

Nutrition Support Group:Regular diet guidance and nutrition support treatment with Nutren based on NRS-2002
Regular Treatment Group:Regular diet guidance only based on NRS-2002.

Sponsors

Zhejiang Provincial People’s Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Pathology or cytology diagnosed with malignant tumors of digestive tract, the main sites are esophageal cancer, gastric cancer and colorectal cancer; 2. aged between 18-70 years, male or female; 3. Receive chemoradiotherapy in our department, had no history of chemoradiotherapy and without any contraindication; 4. no serious metabolic diseases; 5. ECOG PS less than 2; 6. able to eat by mouth; 7. without cognitive impairment and communication barriers, understand and are willing to participate in the study.

Exclusion criteria

Exclusion criteria: 1. received parenteral nutrition; 2. supplemented with albumin, immune enhancer; 3. radiotherapy for less than 20F and palliative chemoradiotherapy; 4. metabolic, endocrine-related disease patients; 5. the mind is not clear, or there are obstacles to communication, can not answer the question; 6. don't want to participate in this study; 7. have a history of immunodeficiency, or suffer from other acquired, congenital immune deficiency disease, or have a history of organ transplantation; 8. mental or cognitive impairment.

Design outcomes

Primary

MeasureTime frame
All grades treatment-related toxicity;

Secondary

MeasureTime frame
Overall survival;Body weight;Quality of life;BMI;Immune related factors;treatment compliance;

Countries

China

Contacts

Public ContactHong'en Xu

Zhejiang Provincial People’s Hospital

xuhongen@hmc.edu.cn+86 0571 85893248

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026