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Effect of saxagliptin and Metformin on bone metabolism in patients with newly diagnosed yype 2 diabetes

Effect of saxagliptin and Metformin on bone metabolism in patients with newly diagnosed yype 2 diabetes

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-17011477
Enrollment
Unknown
Registered
2017-05-24
Start date
2017-10-01
Completion date
Unknown
Last updated
2017-06-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

T2DM

Interventions

Sponsors

Department of Endocrinology; Fuzhou General Hospital of Nanjing Military Area Command
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1) patients with type 2 diabetes mellitus patients, selected in accordance with WHO diagnosis standard in 1999; 2) by the strict diet and exercise control, blood sugar is still not standard (HbA1c 7%~10%); 3) body mass index (BMI) was less than 30kg/ square meters, weight before screening fluctuation range is less than 10% and at least 3 months stability;

Exclusion criteria

Exclusion criteria: 1) acute complications of type 1 diabetes or diabetes, due to pancreatic injury caused by diabetes or secondary diabetes); 2) patients had fractures, osteoporosis disease, is currently taking anti osteoporosis drugs or drugs can cause secondary osteoporosis (Application of glucocorticoids and androgen, calcitonin, the dose of calcium, phosphate and other two known bone metabolic drug treatment); 3) the function of liver and kidney damage or in patients with a history of pancreatitis; 4) with severe cardiovascular disease, immune system, blood system or endocrine system disease; 5) alcoholics; 6) to test drug allergy or taboo; 7) the use of other drugs and drug interactions.

Design outcomes

Primary

MeasureTime frame
glycosylated hemoglobin;FPG;BGP;tPINP;CRP;

Contacts

Public ContactXu Xiangjin

Department of Endocrinology; Fuzhou General Hospital of Nanjing Military Area Command

Xu98111@163.com+86 14759155773

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026