FindTrial
Sign In

The effect of intravenous anesthesia and inhalation anesthesia on neuroinflammation reaction in traumatic brain injury patients

The effect of intravenous anesthesia and inhalation anesthesia on neuroinflammation reaction in traumatic brain injury patients

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-17011313
Enrollment
Unknown
Registered
2017-05-06
Start date
2017-05-01
Completion date
Unknown
Last updated
2017-05-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Traumatic brain injury

Interventions

Intravenous group:anesthesia maintained with propofol
Inhalation group:anesthesia maintained with sevoflurane

Sponsors

Beijing Tiantan Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Traumatic brain injury patients with frontal, tempora or top cerebral contusion, whose glasgow score =8 and need removal of brain tissue, aged 18 to 60 years.

Exclusion criteria

Exclusion criteria: 1. chronic complication; 2. combined with other traumatic injuries(fracture,thoracoabdominal trauma); 3. duration from been injured to operation 18h; 4. blood pressure<90/60mmHg; 6. SpO2<92%.

Design outcomes

Secondary

MeasureTime frame
postoperative complications;—

Primary

MeasureTime frame
key proteins of inflammation signal pathway;brain edema volumn;APACHE II score;glasgow score;—

Countries

China

Contacts

Public ContactCUI Weihua

Beijing Tiantan Hospital, Capital Medical University

13651315600@139.com+86 13651315600

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026