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Study on the mechanism of nicorandil on myocardium and endothelial protection in patients undergoing elective PCI.

Study on the mechanism of nicorandil on myocardium and endothelial protection in patients undergoing elective PCI.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-17011306
Enrollment
Unknown
Registered
2017-05-04
Start date
2017-05-19
Completion date
Unknown
Last updated
2017-05-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

coronary heart disease

Interventions

Treatment Group:Nicorandil 5mg tid
Control Group:none

Sponsors

Fourth Affiliated Hospital of Guangxi Medical University Liuzhou Worker's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: According to the "Chinese percutaneous coronary intervention guide 2012" following patients treated with PCI indication: left main lesion diameter stenosis (IA >50%); proximal left anterior descending artery stenosis 70u/o (IA); with 2 or 3 branches lesion reduced left ventricular function (IB); myocardial ischemia area (myocardial perfusion detection methods showed ischemia area larger than the left ventricular area 10%, IB); no vascular stenosis 70% with angina pectoris, and optimization of drug refractory (IA); have difficulty breathing or chronic heart failure (CHF), and left ventricular ischemia area of more than 10%.

Exclusion criteria

Exclusion criteria: Nicorandil or nitrate drug allergy, glaucoma, severe multivessel emergency PCI surgery or coronary artery bypass grafting, cardiogenic shock, obvious respiratory tract infection and liver and kidney function was abnormal, the left ventricular ejection fraction (LVEF) < 40%, Nicole in recent history.

Design outcomes

Primary

MeasureTime frame
High sensitivity Troponin T;High sensitivity C reactive protein;von willebrand factor;

Countries

China

Contacts

Public ContactMO Fanrui

Fourth Affiliated Hospital of Guangxi Medical University Liuzhou Worker's Hospital

9313902@qq.com+86 13377230700

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026