gastroesophageal reflux disease
Conditions
Interventions
Traditional Chinese medicine group:HeZhongJianPi decoction,two times oral daily, each time 100ml, eight weeks course of treatment
Western medicine group:omeprazole capsules: each 20mg, two times a day orally for eight weeks
Sponsors
Shanghai Municipal Hospital of Shanghai TCM University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patient with gastroesophageal reflux disease more than 1 months; 2. The total RDQ score (a + b) at least 12; 3. Male or female aged 18 to 70 years; 4. Did no receive any formal treatment for system related diseases, including the use of antacids (PPI), antacid (H2RA) and gastric motility drugs and traditional Chinese medicine. Voluntary or receiving a 1 week washout period, drug eluting including PPI, H2RA and gastric motility drug has an impact on the gastrointestinal function of drugs; 5. The voluntary participation in the trial, informed consent, and signed the agreement.
Exclusion criteria
Exclusion criteria: 1. The pregnant or lactating women; 2. The combination of the following diseases: suspected or proven malignant tumor, peptic ulcer, esophageal and gastric or duodenal surgery, Zollinger Ellison syndrome, primary esophageal motility disorders (such as achalasia, scleroderma, primary esophageal spasm), upper gastrointestinal malignant disease, drug-induced esophageal inflammation, pyloric obstruction; 3. The serious cardiovascular disease, liver and kidney dysfunction; 4. There is or psychotic language disorder; 5. It is not partners (that cannot match the diagnosis or not according to the provisions of medication and influence curative effect).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| RDQ;GERD-HRQL; | — |
Secondary
| Measure | Time frame |
|---|---|
| PSQI;HAD; | — |
Countries
China
Contacts
Public ContactLingyun Zhu
Department of Gastroenterology, Shanghai Municipal Hospital of Shanghai TCM University
Outcome results
None listed