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Effect of nebulized hypertonic saline on the treatment of infected acute bronchiolitis in infants

Effect of nebulized hypertonic saline on the treatment of infected acute bronchiolitis in infants

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-17011193
Enrollment
Unknown
Registered
2017-04-20
Start date
2014-10-01
Completion date
Unknown
Last updated
2017-04-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

infected acute bronchiolitis in infants

Interventions

group A :group A were given nebulized 3% hypertonic saline
group B :group B were given nebulized 0.9% hypertonic saline
group C :group C were given regular nebulizer treatment

Sponsors

Department of First Pediatrics, Weifang Maternity and Child Care Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 1 Years

Inclusion criteria

Inclusion criteria: 1. Conforms to the bronchiolitis diagnostic criteria of Practical Pediatrics; 2. Aged 1 months to 12 months; 3. RDAI (Table 1) score of 5 to 15 points (moderate to severe).

Exclusion criteria

Exclusion criteria: 1. Immuno deficiency; 2. Congenital heart or lung disease; 3. Family history of asthma; 4. Gastroesophageal reflux; 5. Premature infant; 6. Cases of severe breathing (respiratory rate>80 breaths/minute, oxygen saturation <88% on room air or need for assisted ventilation); 7. Large patch of the lung lesions on X-ray chest.

Design outcomes

Primary

MeasureTime frame
Respiratory Assessment Change Score;Length of Stay;

Secondary

MeasureTime frame
rate of return to hospital within seven days of discharge;evaluation from parents on the effect of intervention;adverse effect;

Countries

China

Contacts

Public ContactXiaodong Li
kddkewo@126.com+86 13785461396

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026