Early cancer and precancerous lesions of upper gastrointestinal endoscopy
Conditions
Interventions
groupA:20000u pronase and 1g water
groupB:80mg simethicone and 100ml water
groupC:20000u pronase, 80mg simethicone and 100ml water
groupD:100ml water
Sponsors
National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Eligibility
Sex/Gender
All
Age
40 Years to 69 Years
Inclusion criteria
Inclusion criteria: 1. Aged 40 to 69 years old male and female; 2. tested voluntarily, and signed informed consent.
Exclusion criteria
Exclusion criteria: 1. complete pyloric obstruction; 2. active gastrointestinal bleeding; 3. history of upper gastrointestinal surgery; 4. severe heart, liver, and kidney dysfunction and could not accept painless endoscopy; 5. pregnant and lactating women; 6. participated in other clinical studies within a month; 7. psychosis and severe neurosis; 8. allergy to all the drugs used in the test.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| influence on lesion detection rate by different premedication;cost and benefit of different premedication; | — |
Secondary
| Measure | Time frame |
|---|---|
| influence on mucosal visualization by different premedication;influence on examination time by different premedication;influence on flushing water volume by different premedication;Influence on visibility scores by different kinds of activities; | — |
Countries
China
Contacts
Public ContactWang Guiqi
National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Outcome results
None listed