lung cancer
Conditions
Interventions
DO:Dexmedetomidine and oxycodone
Oxycodone:Oxycodone
Sponsors
Shandong Cancer Hospital and Institute
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Aged 18 to 75 years, height 155 to 180 cm, and the ability to understand verbal and written Mandarin Chinese, no history of mental illness, no drug abuse and other analgesics such as opioids, NSAIDS, or traditional Chinese medicine or antibiotics.
Exclusion criteria
Exclusion criteria: 1. included an intolerance for 1-lung ventilation, a long history of opioid analgesic or NSAID use, tranquilizer use, psychiatric disorders, bradycardia with cardiac conduction or rhythm abnormalities, a history of rib fracture, or previous trauma or lung surgery on the same side as the planned lobectomy. 2. Individuals subsequently were excluded from the study if they required an open thoracotomy conversion or reoperation due to postoperative bleeding or other complications.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS score;consumption of oxycodone;IL-6;IL-10;HMGB1;TNFalpha; | — |
Secondary
| Measure | Time frame |
|---|---|
| Ramsay Sedation Score;Satisfaction with analgesia; | — |
Countries
China
Contacts
Public ContactWang Xiuqin
Shandong Cancer Hospital and Institute
Outcome results
None listed