Irritable Bowel Syndrome
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) IBS-D Rome III diagnostic criteria; (2) Age is 18-70 years old; (3) duration of more than 6 months; (4) lack of morphological changes and biochemical abnormalities that can explain the symptoms; (5) Baseline IBS-SSS integral = 75 points; (6) No medication for IBS was used for at least 2 weeks prior to treatment (except for emergency treatment), acupuncture treatment against IBS was not received in the last 3 months, and no other clinical investigators were present; (7) signed informed consent, voluntary participation in the study.
Exclusion criteria
Exclusion criteria: (1) meet IBS-M, IBS-U, IBS-C Rome III diagnostic criteria; (2) have intestinal organic disease, or affect the gastrointestinal motility of the systemic diseases (such as gallbladder pancreatitis, hyperthyroidism, diabetes, chronic renal insufficiency, neurological disease); (3) combined with the cardiovascular system, liver, kidney, hematopoietic system, mental illness, cognitive dysfunction and other serious primary disease; (4) history of abdominal or rectal surgery; (5) often taking the effect of gastrointestinal motility or change the intestinal function of drugs or preparations; (6) the age of 18 years of age or older; (7) pregnancy, lactation, postpartum = 12 months and allergy; (8) the use of other treatment or taking other drugs, affect the efficacy or safety of those who judge; (9) patients refused to observe the group or contain other unstable factors, such as: not taking the provisions of other effects of observation of the drug can not determine the efficacy or incomplete information; (10) the installation of pacemakers, metal allergies or severe fear of the needle; (11) to participate in other subjects test subjects.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum miroRNA; | — |
Countries
China
Contacts
Jiangsu Provincial Hospital of TCM