Iriitable Bowel Syndrome
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) IBS-D Rome III diagnostic criteria; (2) Age is 18-70 years old; (3) lack of morphological changes and biochemical abnormalities that can explain symptoms; (4) Baseline IBS-SSS integral = 75 points; (5) did not use any treatment of IBS at least 2 weeks before treatment (except for emergency treatment), and did not receive acupuncture treatment against IBS for nearly three months; (6) did not participate in other ongoing clinical researchers; (7) signed informed consent, voluntary participation in the study
Exclusion criteria
Exclusion criteria: (1) intestinal organic disease, or affect the digestive tract of the systemic diseases (such as gallbladder pancreatitis, hyperthyroidism, diabetes, chronic renal insufficiency, neurological disease); (2) combined with the cardiovascular system, liver, kidney, hematopoietic system, mental illness, cognitive dysfunction and other serious primary disease; (3) a history of abdominal or rectal surgery; (4) often taking the effect of gastrointestinal motility or change the intestinal function of drugs or preparations; (5) the age of 18 years of age or older; (6) pregnancy, lactation, postpartum = 12 months and allergies; (7) the use of other treatment or taking other drugs, affect the efficacy or safety of those who judge; (8) patients refused to observe the group or contain other unstable factors, such as: not taking the provisions of other effects of observation of the drug can not determine the efficacy or incomplete information; (9) the installation of pacemakers, metal allergies or severe fear of the needle;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Colon tissue TRPV1 protein concentration;microRNA-199; | — |
Countries
China
Contacts
Jiangsu Provincial Hospital of TCM