Transsphenoidal resection of pituitary tumor
Conditions
Interventions
Group low dose Dexmedetomidine:Low dose of Dexmedetomidine
Group high dose Dexmedetomidine:High dose Dexmedetomidine
Control group:Normal saline
Sponsors
Department of Anesthesiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 18-65 years old, ASA 1-2, scheduled to receive transsphenoidal resection of pituitary tumor under general anesthesia, informed consent signed
Exclusion criteria
Exclusion criteria: BMI=30kg/m2, operation time> 3 hours, allergy to dexmedetomidine, the application of monoamine oxidase inhibitors or adrenergic receptor blockers, uncontrolled hypertension, cardiac block of 2 degree and above, Liver and kidney disease (2 times the relevant markers),taking antipsychotics, opioid abuse, and patients who can not cooperate with this trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| emergence agitation; | — |
Secondary
| Measure | Time frame |
|---|---|
| quality of recovery;nausea and vomiting;pain; | — |
Countries
China
Contacts
Public ContactTANG Shuai
Department of Anesthesiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences
Outcome results
None listed