infertility
Conditions
Interventions
GnRHa+HRT-FET:GnRHa+HRT-FET
NC/LE/HMG/HRT-FET:NC/LE/HMG/HRT-FET
Sponsors
The Shanghai Ninth People's Hospital affiliated of Shanghai JiaoTong University of medical school
Eligibility
Sex/Gender
Female
Age
20 Years to 38 Years
Inclusion criteria
Inclusion criteria: 1. patients with active endometriosis aged 20-38 years; 2. more than 2D3 high-quality embryos frozen (=2D3 6 cell grade I and II) or a blastocyst (4BB and above); 3. clinical manifestations and auxiliary examination of active endometriosis: (1) endometriotic cysts recurrence after laparoscopy or laparotomy before IVF; (2) increased dysmenorrhea or tenderness nodules by gynecological examination after endometriotic cysts surgery by laparoscopy or laparotomy before IVF; (3) increased CA125 after endometriotic cysts surgery by laparoscopy or laparotomy before IVF; (4) ovarian endometriomas that were aspirated and identified as multiple chocolate cysts (=1-3cm) or a single chocolate cyst(=3cm)(unilateral or bilateral) during ovulation monitoring or at the time of oocyte retrieval.
Exclusion criteria
Exclusion criteria: 1. Hydrosalpinx; 2. polycystic ovarian syndrome (PCOS); 3. adenomyosis (AM) diagnosed by laparoscopic or laparotomy or disordered myometrial echo confirmed by ultrasound examination, mild adenomyosis by MRI diagnosis; 4. uterine malformations; 5. severe intrauterine adhesions; 6. endometrium thickness <7mm on transplantation day; 7. recurrent abortions =3; 8. clinically significant systemic disease such as renal failure.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| clinical pregnancy rate;implantation rate;cancellation rate;live birth rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| cumulative pregnancy rate;abortion rate;ectopic rate;multiple pregnancy rate;average number of visits; | — |
Countries
China
Contacts
Public ContactYanping Kuang
Shanghai Nineth People's Hospital
Outcome results
None listed