Diabetic Kidney Disease
Conditions
Interventions
treatment group:Hu-lu-ba-wan
treatment group:Hu-lu-ba-wan with low dose
control group:conventional treatment
Sponsors
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
25 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients with type 2 diabetes mellitus; 2. Diabetic kideny disease at stage III; 3. Comsumptive thirst with Yang deficiency syndromes as follows: fear of cold, coldness in waist and knees, swelling of face and feet, plump tongue and white fur, deep and thready and moderate pluse (Those who have at lease two syndromes can be disgnosed); 4. Aged between 25-70 years old, male and female; 5. Sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with type 1 diabetes mellitus; 2. Serum albumin 140/90mm/Hg; 4. Severe primary heart, hepatic and hematologic disease or other severe disease, such as ALT >2*N (N: upper normal limit); 5. Uncontrolled infection and serious electrolyte disorder; 6. Increase of urinary albumin excretion caused by primary or secondary kidney disease , hypertension, heart failure, urinary tract infection; 7. Mental illness; 8. Pregnant and lactating women or women preparing for pregnancy; 9. Patients of allergic constitution, or patients allergic to two or more drugs, or patients allergic to the drugs used in the trial; 10. Patients who took part in other clinical drugs trial in the past three months; 11. Disabled patients; 12. History of alcohol or drug abuse; other conditions judged by the trialist that may influence the follow-up, such as the frequent change of working environment; 13. Patients who have to be treated with hormone; 14. Uncontrolled hypertension or secondary hypertension; 15. Subjects who are regarded as with poor compliance that could not complete the research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Traditional Chinese medicine Chinese menopause rating scale;Ratio of urine microalbumin to creatine;Serum free fatty acids; | — |
Secondary
| Measure | Time frame |
|---|---|
| Glucose metabolic index: FBG, HbAlc;TC, TG, HDL-C, LDL-C;Blood routine examination;Urine routine examination;Liver function;Renal function;Electrocardiogram; | — |
Countries
China
Contacts
Public ContactFuer Lu
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed