lung injury induced by one lung ventilation
Conditions
Interventions
control group:no
EPO group:EPO
Sponsors
Department of Anaesthesia, The 2nd Affiliated Hospital of Harbin Medical University, Harbin, China
Eligibility
Sex/Gender
All
Age
25 Years to 65 Years
Inclusion criteria
Inclusion criteria: 60 patients aged 20 to 60 years, ASA I-II which undergoing the lobectomy for lung cancer
Exclusion criteria
Exclusion criteria: smoking cessation 35 kg/m2, abnormal lung function (vital capacity or forced expiratory volume in 1 s 10.0×10^9/L), cardiac arrhythmia classified as Lown IIb, or a history of or current non-lung cancer, chronic lung disease (chronic pneumonia, bronchitis, pneumoconiosis, silicosis, or asthma), pleural effusion, or pulmonary hypertension (>30 mmHg).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TNF-a in BALF; | — |
Secondary
| Measure | Time frame |
|---|---|
| peak, plat;arterial blood analysis;lung compliance;IL-1 in BALF;IL-6 in BALF;IL-6 in BALF;IL-10 in BALF; | — |
Countries
China
Contacts
Public ContactWei Gao
Department of Anaesthesia, The 2nd Affiliated Hospital of Harbin Medical University, Harbin, China
Outcome results
None listed