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Probiotics as adjunct to periodontal therapy.

Effect of adjunctive probiotic therapy on periodontal pocket microbiomes: A randomized placebo controlled parallel arm study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-17010526
Enrollment
Unknown
Registered
2017-01-26
Start date
2017-02-01
Completion date
Unknown
Last updated
2020-05-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontitis

Interventions

2:Non surgical periodontal therapy and placebo probiotic

Sponsors

Faculty of Dentistry, The University of Hong Kong
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Adult patients diagnosed with chronic periodontitis, that is with at least 2 non-adjacent teeth with probing depth =5 mm and evidence of radiographic bone loss, with at least 10 teeth excluding third molars and good systemic health.

Exclusion criteria

Exclusion criteria: Pregnant or lactating females. Subjects with antibiotic therapy, probiotics or anti-inflammatory drugs within past 6 months. Radiation therapy in the head and neck area, HIV, Tuberculosis, hepatitis or other infectious diseases or uncontrolled diabetes, ischaemic heart disease, thyroid disorders or psychological problems.

Design outcomes

Primary

MeasureTime frame
Changes in Periodontal Probing Depth;Changes in Clinical Attachment Level;—

Secondary

MeasureTime frame
Changes in Percentage of Sites with Bleeding on Probing;changes in the percentage of sites with visible plaque;—

Countries

China

Contacts

Public ContactGeorgios Pelekos

Faculty of Dentistry, The University of Hong Kong

george74@hku.hk+852 2859 0343

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 1, 2026