urethral stricture
Conditions
Interventions
1st group:Lingual mucosa graft (LMG)
2nd group:Buccal mucosa graft (BMG)
3rd group:LMG combined with BMG
Sponsors
Shanghai Sixth People's hospital
Eligibility
Sex/Gender
Male
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. aged 18 to 45 years; 2. Without a history of open urethral surgery; 3. The patient/family members informed and sign the informed consent; 4. estimate the anterior urethral stricture length < 2.5 cm by the preoperative urinary tract imaging and Urethrocystoscope;
Exclusion criteria
Exclusion criteria: 1. with a history of open urethral surgery or the urethra incision or urethra expansion history for many times; 2. with a history of severe hypertension; 3. with a history of diabetes; 4. with a history of the blood coagulation dysfunction or anticoagulant drugs; 5. with liver or kidney dysfunction; 6. Patients who can not cooperate with treatment; 7. mental disorder or nerve dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Urinary flow rate;urethrography; | — |
Secondary
| Measure | Time frame |
|---|---|
| Difficulty in opening the mouth;Pain at graft harvest site;Difficulty in tongue protrusion;urethrocutaneous fistulas;Recurrence of urethal stricture; | — |
Countries
China
Contacts
Public ContactYuemin Xu
Shanghai Sixth People's Hospital
Outcome results
None listed