nausea and vomiting
Conditions
Interventions
P:propofol (20 mg bolus and 1.0 mg/kg/h)
C:lipid elmulsion 2ml iv, then o.iml/kg/h
Sponsors
West China Second Hospital, Sichuan University, West China Women's and Children's Hospital
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: Patients aged 20-40 years, with physical statues I and II with full term pregnancy underging elective caesarean section under spinal anesthesia.
Exclusion criteria
Exclusion criteria: Patients with allergy or hypersensitivity to granisetron, propofol or fat emulsion; history of nausea and vomiting within 24h before CD; history of gastrointestinal or psychiatric disease, motion sickness, smoking,PONV; morbid obesity(weight>85kg); consumption of drugs such as opioids, antimetics, H2-antagonist, phenothiazines and/or corticosteroids within 24h before the study period; any chronic medical or surgical disorders complicating the pregnancy; and conditions contraindicating regional anesthesia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| nausea and vomiting; | — |
Secondary
| Measure | Time frame |
|---|---|
| blood pressure;heart rate;headache;rescue antiemetic;chest distress; | — |
Countries
China
Contacts
Public ContactYanmei Bi
West China Second Hospital, Sichuan University, West China Women's and Children's Hospital
Outcome results
None listed