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The therapeutic evaluation of acupuncture for post-stroke non-fluent aphasia based on multi-modal MRI

The therapeutic evaluation of acupuncture for post-stroke non-fluent aphasia based on multi-modal MRI

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-17010488
Enrollment
Unknown
Registered
2017-01-20
Start date
2015-07-01
Completion date
Unknown
Last updated
2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aphasia

Interventions

Treatment Group:Acupuncture

Sponsors

Dongzhimen Hospital affiliated to Beijing University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Diagnosed as stroke; 14 days to 6 months after stroke onset; aged from 35 to 80 years; 2. Native language is Chinese; right-handed; 3. Showing aphasia syndrome; diagnosed as non-fluent aphasia by China Rehabilitation Research Center Aphasia Examination (CRRCAE); Boston Diagnostic Aphasia Examination (BDAE) severity rating scale = 2; 4. Primary school and above education; 5. Clear consciousness; no cognition impairment; 6. Capable of cooperating 20 minutes MRI examination.

Exclusion criteria

Exclusion criteria: 1. Serious dysarthria, auditory perceptual impairments or cognition disorder, which do not allow the patients to cooperate with batteries examination; 2. Language impairments due to disturbance of consciousness or low Intelligence Quotien(IQ); 3. Learning disability and language function defect due to congenital or childhood diseases; 4. Serious function damage of organs like heart, liver and kidney, and researchers consider not suitable to the study; 5. Patients who are accepting transcranial direct current stimulation therapy, or taking piracetam, donepezil, memantine, bromocriptine, galanthamine, and are not allowed to stop the therapy; 6. Existence of contraindication of MRI, for example, cardiac pacemaker operation, percutaneous coronary intervention (PCI) or Coronary Artery Bypass Grafting(CABG).

Design outcomes

Primary

MeasureTime frame
Severity of Aphasia;

Secondary

MeasureTime frame
Language Function;Magnetic Resonance Imaging;Cognitive Ability;Neurological Deficits;Activity of Daily Living;Quality of Life;Severity of Depression;

Countries

China

Contacts

Public ContactYing Gao, Jingling Chang

Dongzhimen Hospital affiliated to Beijing University of Chinese Medicine

gaoying973@126.com+86 010-84013209

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026