Respiratory and cardiac
Conditions
Interventions
1:Neuromuscular Electrical Stimulation
Sponsors
Physiotherapy Department, Queen Elizabeth Hospital, Hospital Authority, Hong Kong
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Adult patients at ICU who are on mechanical ventilator due to acute respiratory failure, trauma, sepsis, and acute coronary syndromes. 2.Cardiorespiratory stability: FiO2= 55% & noradrenaline = 0.2 ug/kg/min.
Exclusion criteria
Exclusion criteria: 1. Conditions contraindicated for NMES such as skin allergy, open wounds or superficial metal implants over stimulation sites, etc.; 2. Trauma or surgery of leg, pelvis, or lumbar spine; 3. Open abdominal wounds; 4. Extreme obesity (BMI > 35kg/m2); 5. Serious bedsore or venous ulcers; 6. Pre-existing diagnosis causing neuromuscular weakness; 7. Acute stroke, Status epilepticus; 8. Coagulation disorders (INR>1.5 or platelets 150mL/kg body weight; - Respiratory rate >30 BPM; - On vasopressive support (noradrenaline > 0.2µgkg-1.min-1, dobutamine > 8µg.kg-1.min-1). 11. Acute renal failure with increased serum creatinine level (normal result is 0.7 to 1.3 mg/dL for men and 0.6 to 1.1 mg/dL for women); 12. APACHE II score = 30.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Muscle thickness;Muscle cross sectional area; | — |
Secondary
| Measure | Time frame |
|---|---|
| quality of life;FSS-ICU functional staus; | — |
Countries
China
Contacts
Public ContactDr. Gabriel Y.F. Ng
Hospital Authority, Hong Kong
Outcome results
None listed