dry eye
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Meeting the diagnosis criteria of dry eye disease; 2. Unisex; 3. Volunteer participant with fine compliance and having signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. aged less than 18 years old; 2. use of any eye drops and ointment 2 weeks before the study, and squeezing eyes or rubbing eyelids 1 hour before and during the study; 3. wearing contact lens on the day of the study; 4. malformation of cornea, conjunctiva or eyelid and hypophasis; 5. ocular acute inflammation and use of topical or systemic drugs for treatment; 6. allergic conjunctivitis; 7. eye surgery done within the past 3 months; 8. autoimmune disease; 9. allergic to sodium hyaluronate formulations.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| lipid layer thickness;SPEED questionnaire score;tear break-up time;Schirmer ? test;tear meniscus height;fluorescein staining;Marx line score;lid wiper;meibomian glands dropout;meibomian gland secretion score;meibomian gland expressilibity;blink rate;eyelid margin abnormality score; | — |
Countries
China
Contacts
Zhongshan Ophthalmic Center, Sun Yat-sen University