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Correlation between tear film lipid layer and tear functions and the effects of artificial tears on lipid layer in dry eye patients

Correlation between tear film lipid layer and tear functions and the effects of artificial tears on lipid layer in dry eye patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-17010483
Enrollment
Unknown
Registered
2017-01-19
Start date
2016-05-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

dry eye

Interventions

Sponsors

Zhongshan Ophthalmic Center, Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Meeting the diagnosis criteria of dry eye disease; 2. Unisex; 3. Volunteer participant with fine compliance and having signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. aged less than 18 years old; 2. use of any eye drops and ointment 2 weeks before the study, and squeezing eyes or rubbing eyelids 1 hour before and during the study; 3. wearing contact lens on the day of the study; 4. malformation of cornea, conjunctiva or eyelid and hypophasis; 5. ocular acute inflammation and use of topical or systemic drugs for treatment; 6. allergic conjunctivitis; 7. eye surgery done within the past 3 months; 8. autoimmune disease; 9. allergic to sodium hyaluronate formulations.

Design outcomes

Primary

MeasureTime frame
lipid layer thickness;SPEED questionnaire score;tear break-up time;Schirmer ? test;tear meniscus height;fluorescein staining;Marx line score;lid wiper;meibomian glands dropout;meibomian gland secretion score;meibomian gland expressilibity;blink rate;eyelid margin abnormality score;

Countries

China

Contacts

Public ContactZhichong Wang

Zhongshan Ophthalmic Center, Sun Yat-sen University

wzc001@hotmail.com+86 18922103685

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026