FindTrial
Sign In

Effects of dexmedetomidine on hemodynamics during perioperative period

Effects of dexmedetomidine on hemodynamics during perioperative period

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-17010423
Enrollment
Unknown
Registered
2017-01-13
Start date
2014-07-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Perioperative hemodynamics

Interventions

P+ DEX group:propofol for anesthesia maintenance, a loading dose of dexmedetomidine
S+ DEX group:sevoflurane for anesthesia maintenance, a loading dose of dexmedetomidine
P+NS group:propofol for anesthesia maintenance, volume-matched normal saline
S+NS group:sevoflurane for anesthesia maintenance, volume-matched normal saline

Sponsors

Xuzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Between 18 and 65 years old; American Society of Anesthesiologists (ASA) grade I or II; operation time expected to more than 1h; baseline blood pressure lower than 160/90mmHg; heart rate greater than or equal to 60 bpm/ min; no liver and renal dysfunction and no abnormal anesthesia operation history.

Exclusion criteria

Exclusion criteria: ECG showed sinus tachycardia, sick sinus syndrome and atrioventricular block; use of cardioactive or antihypertensive medication in the preoperative period

Design outcomes

Primary

MeasureTime frame
blood pressure;heart rate;—

Countries

China

Contacts

Public ContactHan Yuan

Xuzhou Medical Univetsity

374198873@qq.com+86 13852470693

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 24, 2026