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GnRHa preconditioning plus hormonal substitution protocol versus hormonal substitution protocol alone for frozen–thawed embryo transfer in patients with polycystic ovary syndrome: A prospective, randomized, controlled tial

GnRHa preconditioning plus hormonal substitution protocol versus hormonal substitution protocol alone for frozen–thawed embryo transfer in patients with polycystic ovary syndrome: A prospective, randomized, controlled tial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-17010414
Enrollment
Unknown
Registered
2017-01-13
Start date
2017-01-16
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

polycystic ovary syndrome

Interventions

B:hormonal substitution protocol
A:a GnRH agonist plus exogenous hormone stimulation protocol

Sponsors

Northwest Women and Children's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. menstrual abnormalities (irregular uterine bleeding, oligomenorrhea, or amenorrhea) combined with either hyperandrogenism or polycystic ovaries, as validated in our Chinese population; 2. Polycystic ovaries were defined as the presence of either an ovary containing 12 or more antral follicles measuring 2 to 9 mm in diameter or an increased ovarian volume (>10 cm3); 3. Hyperandrogenism was diagnosed on the basis of either hirsutism or hyper-androgenemia; Other causes of hyperandrogenism and ovulation dysfunction including tumors, congenital adrenal hyperplasia, hyperprolactinemia, and thyroid dysfunction will be ruled out.

Exclusion criteria

Exclusion criteria: 1. Fallopian tube effusion; 2. recurrent spontaneous abortion (defined as three or more previous spontaneous pregnancy losses); 3. congenital or acquired uterine malformations

Design outcomes

Primary

MeasureTime frame
Live birth rate;Clinical pregnancy rate;Early abortion rate;

Contacts

Public ContactJuanzi SHI

Northwest Women and Children's Hospital

shijuanzi@126.com+86 18602991568

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026