Cervical cancer
Conditions
Interventions
intervention:pelvic active bone marrow-sparing
Control 1:pelvic bone marrow-sparing
Control 2:without pelvic bone marrow-sparing
Sponsors
The Second People's Hospital of Yibin, Yibin, Sichuan
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 70 years old; 2. Pathologically confirmed cervical cancer,FIGO staging locally advanced cervical cancer (1B2/2A2/2B and above); 3. ECOG performance status 0 - 1; 4. more than the expected survival time in One year; 5. WBC=4×10^9/L, ANC=2×10^9/L Hemoglobin=110g/L, Platelets =100×10^9/L; Bilirubin <=2*ULN; ALT and AST <=2.5*ULN; BUN <=1.5*ULN; Creatinine<=1.5*ULN; 6. Signed study-specific informed consent.
Exclusion criteria
Exclusion criteria: 1. Any current or previous chemotherapyor pelvic radiotherapy for this tumour; 2. Patients who have any cause of peripheral blood cell abnormalities; 3. Patients who have severe uncontrolled internal diseases; 4. Patients who have A history of mental illness; 5. Patients who are pregnant or lactating; 6. Patients who did not sign study-specific informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| acute hematologic toxicity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Acute radiation enteritis;dose habituation index;conformal index;Cycles of chemotherapy;overall survival;progression free survival; | — |
Countries
China
Contacts
Public ContactWang Shanbing
The Second People's Hospital of Yibin, Yibin, Sichuan
Outcome results
None listed