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Study of the effect of different anesthesia selection on the prognosis of patients with glioma

Study of the effect of different anesthesia selection on the prognosis of patients with glioma

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-16010180
Enrollment
Unknown
Registered
2016-12-18
Start date
2017-01-01
Completion date
Unknown
Last updated
2017-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glioma

Interventions

TIVA group:TIVA, propofol
Inhalational anesthesia group:Inhalational anesthesia, sevoflurane

Sponsors

Xuanwu Hospital of CCMU
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. American Society of Anesthesiologists (ASA) physical status I-II; 2. Aged 18~65 years old; 3. Suffering from intracranial space-occupying lesions and will be given an elective resection; 4. Without severe complication of other systems; 5. Patients join in the research for voluntary.

Exclusion criteria

Exclusion criteria: 1. Received radiotherapy or chemical therapy within 6 months; 2. Using hormone for long period; 3. Companied by severe complications of other systems; 4. Pathological diagnosis is not gliomas; 5. Experienced extremely unstable situations during the operation; 6. Patients refused or quitted the research.

Design outcomes

Primary

MeasureTime frame
The gene copy number of prognosis related genes of glioma;—

Secondary

MeasureTime frame
age;gender;Body Mass Index;Blood pressure;MAP;PPV;HR;SpO2;BIS value;PET CO2;Temperature;Length of surgery;ASA status;NYHA functional class;MET class;state of consciousness before operation;complication of other systems;tumor location;tumor size;primary diagnosis;length of Anesthesia;time of tumor exposure to anesthetics;infusion volume;lost volume;postoperative consciousness;whether extubation;postoperative whereabouts;fever degree of 1st 2nd 3rd day postoperation other complications;NRS score of 1st 2nd 3rd day postoperation other complications;degree of brain edema postopeartion;incidence of complications of CNS;incidence of complications of circulatory system;incidence of complications of respiratory system;incidence of complications of digestive system;incidence of complications of urinary system;hospital stay;pathological results;survival rate and mortality;plasma concentration of inflammatory factors;—

Countries

China

Contacts

Public ContactZHAO LEI

Xuanwu Hospital of CCMU

zhaoalei@sina.com.cn+86 13811035886

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026