Parkinson's Disease
Conditions
Interventions
propofol-remifentanyl group:propofol-remifentany infusion for monitored anesthesia care during awake deep brain stimulation surgery
dexmedetomidine group:dexmedetomidine infusion for monitored anesthesia care during awake deep brain stimulation surgery
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients aged=18 years, ASA physical status I-III, undergoing selective deep brain stimulation, agree to inform consent and follow-up
Exclusion criteria
Exclusion criteria: Patients with body mass index (BMI)> 30kg/m2 or 180mmHg and / or diastolic blood pressure> 110mmHg). Severe cardiovascular disease and patients known or suspected allergy to anesthetics (propofol, remifentanil, dexmedetomidine and so on).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the ability of patient to cooperate in macrostimulation testing;Modified OAA/S scale;Postoperative relief of disease in patients; | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS pain scores;Total postoperative consumption of analgesic,in mg,of through 24 hours;the incidence of vomiting and nause in the first 24h after operation; | — |
Countries
China
Contacts
Public ContactLi Yu
West China Hospital, Sichuan University
Outcome results
None listed