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Magnetic resonance imaging study of hyperbaric oxygen treatment on cognitive dysfunction after traumatic brain injury

Magnetic resonance imaging study of hyperbaric oxygen treatment on cognitive dysfunction after traumatic brain injury

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-16010091
Enrollment
Unknown
Registered
2016-12-05
Start date
2015-04-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Traumatic brain injury

Interventions

HBO:hyperbaric oxygen,conventional surgery and rehabilitation
Sham:Conventional surgery and rehabilitation

Sponsors

Department of Rehabilitation Medicine, Fuzhou General Hospital of Nanjing Military Command, PLA. Fuzhou, Fujian, 350025
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 55 Years

Inclusion criteria

Inclusion criteria: 1. Be diagnosed with traumatic brain injury by CT or(and) MRI; 2. MMSE=26; 3. Aged 18 to 55 years; 4. During the post-injury recovery stage, lasting less than six mouths; 5. First brain injury; 6. BDI<14; 7. Information consent, participate the trial voluntary.

Exclusion criteria

Exclusion criteria: 1. previous disease history: brain trauma, surgery, cerebral tumor or other brain lesions; 2. Serious words, vision, hearing impairment or mental disorders; 3. Past cognitive disorder or drug influenced on cognition; 4. MRI contraindications (non-removable denture, cardiac pacemaker, electronic cochlear implants, claustrophobia); 5. A history of drug abuse, alcohol; 6. patients with epilepsy; patients with severe heart, liver, or renal dysfunction; and patients with blood disorders; 7. Pregnancy or breast-feeding women; 8. For other clinical subjects.

Design outcomes

Primary

MeasureTime frame
MMSE;

Secondary

MeasureTime frame
cognitive function;fMRI;

Countries

China

Contacts

Public ContactPeng Huiping

Department of Rehabilitation Medicine, Fuzhou General Hospital of Nanjing Military Command, PLA. Fuzhou, Fujian

361140072@qq.com+86 13600823060

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026