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Effect of therapeutic hypercapnia on cerebral oxygenation in patients undergoing shoulder surgery in the beach chair position

Effect of therapeutic hypercapnia on cerebral oxygenation in patients undergoing shoulder surgery in the beach chair position

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-16010085
Enrollment
Unknown
Registered
2016-12-05
Start date
2017-01-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

shoulder disease

Interventions

Control group:maintain the endtidal pressure of carbon dioxide( PETCO2) 35-40 mmHg
Therapeutic hypercapnia group:maintain the endtidal pressure of carbon dioxide( PETCO2) 45-50 mmHg

Sponsors

The First Affiliated Hospital of Anhui Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 80 years old, Male or female; 2. ASA grade I or II, NYHA class I-II; 3. normal liver function and renal function; 4. The first shoulder surgery patients; 5. Patient is able to understand the trail and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. orthostatic hypotension or poorly controlled hypertension; 2. pre-existing history of cerebrovascular disease; 3. pre-existing history of pulmonary disease; 4. symptomatic cardiovascular disease.

Design outcomes

Primary

MeasureTime frame
the regional cerebral saturation(rSO2);cerebral desaturation events(CDE);nausea;vomiting;—

Countries

China

Contacts

Public ContactGu Erwei

The First Affiliated Hospital of Anhui Medical University

ay_guew_mz@163.com+86 13966663478

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026