Pain after day surgery
Conditions
Interventions
control group:Tramadol
Sponsors
Xiangya Hospital, Central South University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Aged 18 years to 50 years old, male and female; ASA I-II; breast surgery (non-radical mastectomy), thyroid surgery, hysteroscopic surgery, laparoscopic cholecystectomy, operation time 3 points. ICF was signed. BMI 18 to 29.
Exclusion criteria
Exclusion criteria: The patients known to allergy to the main drug or any kind of excipient,or known to allergy to opioids.Acute (slow) alcoholism, a history of neurological diseases. A history of chronic pain. Drug addiction and alcoholism. Paralytic ileus. Increased intracranial pressure or head injury.A history of Long-term use of opioids. Hypotension, hypothyroidism, asthma (avoid use during episodes). Prostatic hypertrophy and epilepsy patients. Taking monoamine oxidase inhibitors or antidepressants in 15 days. Preoperative liver and kidney function: ALT,AST,BUN,Cr abnormalities(ALT and AST greater than 1.5 times the upper limit of normal, BUN and Cr higher than the upper limit of normal).Coronary heart disease, bronchial asthma, poorly controlled or very difficult to control hypertension: SBP=160mmHg or DBP=100mmHg. Respiratory insufficiency, respiratory failure.Patients can not properly express wishes. Poor compliance, cant complete the trial according to the study protocol. Participated in the other tries in 30 days.Pregnant women, maternal, pregnancy test positive women of childbearing age.Coagulation dysfunction. The patients whom investigators did not consider appropriate to participate the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS scores;Analgesia effectiveness; | — |
Secondary
| Measure | Time frame |
|---|---|
| blood pressure;Respiratory rate;heart rate; | — |
Countries
China
Contacts
Public ContactGuo Qulian
Xiangya Hospital, Central South University
Outcome results
None listed