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A double-blind randomized cross-over study of a medium-chain fatty acid diet in the adjuvant therapy of Alzheimer's disease

A double-blind randomized cross-over study of a medium-chain fatty acid diet in the adjuvant therapy of Alzheimer's disease

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-16009737
Enrollment
Unknown
Registered
2016-11-04
Start date
2016-11-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alzheimer's disease

Interventions

1 group:diet A and diet B
2:diet B or diet A

Sponsors

Chinese PLA General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Alzheimer's disease was diagnosed using the National Institute of Neurological Disorders and the Alzheimer's Disease and Associated Diseases (NINCDS-ADRDA) criteria and the MMSE evaluation scores of 14 to 24 points; 2. Survival is expected to be more than 1 year; 3. No tumor, congenital or acquired immunodeficiency disease, congestive heart failure, angina pectoris, myocardial infarction, uncontrolled high blood pressure or heart rhythm, arrhythmia and other serious heart disease, active hepatitis, liver cirrhosis and other serious liver disease, no one kind of glomerulonephritis, nephrotic syndrome, uremia and other serious kidney disease; 4. Blood, ECG in normal Range, liver and kidney function measured value of = 1.5 times the normal value of serum triglyceride measured value of the upper limit of = 2 times the normal value of the upper limit of serum cholesterol measurement = 2 times the normal value; 5. can be follow-up, good compliance.

Exclusion criteria

Exclusion criteria: Alzheimer's Disease but the MMSE evaluation scores less than 14 points or over the 24 points.

Design outcomes

Primary

MeasureTime frame
Cognitive Scale Score;

Secondary

MeasureTime frame
Serum ketone body related indicators;Serological fatty acid metabolites;Blood biochemical indicators;

Countries

China

Contacts

Public ContactXu Qing

Chinese PLA General Hospital

aqing_930@163.com+86 15011493918

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 1, 2026