Cancer
Conditions
Interventions
2:BDL and chemotherapy
Sponsors
Shanghai Tenth People's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Diagnosed as cancer by histology or cytology; 2. male and female aged 18 years and elder; 3. ECOG physical status score = 1; 4. No significant heart, liver, kidney, digestive tract, metabolic disorders, nervous system diseases. 5. No history of allergies; 6. The trial unit should sign informed consent with the volunteer.
Exclusion criteria
Exclusion criteria: 1. No drugs with immune stimulation effects were used in 2 weeks before BDL treatment; 2. Patients with renal and liver dysfunction (ALT and AST=1.5/2 times of normal rangeserum creatinine and blood urea nitrogen =1.2 times of the normal range; 3. Mentally ill; 4. To be pregnant, pregnant or lactating women; 5. Allergy to our drug; 6. A major active infection, or the investigator determines that there is significant blood, kidney, metabolic, gastrointestinal or endocrine dysfunction; 7. Persons with a history of drug, drug or alcohol abuse; 8. Have a history of immunodeficiency, including HIV positive or suffering from other acquired, congenital immunodeficiency disease, or a history of organ transplantation; 9. In acute and chronic tuberculosis, hepatitis infection period; 10. Other circumstances that the investigator considers unsuitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change of cancer-related inflammatory factors concentrationTGF-ß, IL-6, IL-1ß, TNF-a; | — |
Secondary
| Measure | Time frame |
|---|---|
| Bone marrow suppression rate;Tumor marker change; | — |
Countries
China
Contacts
Public ContactFANG JUEMIN
Shanghai Tenth People's Hospital
Outcome results
None listed