Delayed graft function in kidney transplantation
Conditions
Interventions
HRS Group:Hydrogen-rich solution
Controlled group:regular solution
Sponsors
Institute of Organ Transplantation, Tongji Hospital, Tongji Medical School, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. DCD donor aged 18-65 years male or female; 2. Last sereum creatinine of DCD donors before donation should be >150umol/L; 3. Patienst would recieve the first time renal translantation due to uremia; 4. Recipients aged 18-60 years male or female; 5. Patients willing to voluntee to participate, and to sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Pateints who do not meet the inclusion criteria; 2. Patients who are HLA presensitized before renal transplantation,including patients either with positive PRA or a history of pretransplantation; 3. Patients who have high risk of recurrence disease after renal transplantation (FSGS,IgA nephropathy); 4. Patients who would undergo multi-organ transplantation; 5. Patients who are pregnant orlactating.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| rate of Delayed Graft Function(DGF); | — |
Secondary
| Measure | Time frame |
|---|---|
| serum creatinine;eGFR;HMGB-1; | — |
Countries
China
Contacts
Public ContactGang Chen
Institute of Organ Transplantation, Tongji Hospital, Tongji Medical School, University of Huazhong Science and Technology
Outcome results
None listed