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Respiratory mechanics and gas exchange during one-lung ventilation for thoracic surgery: the effects of end-inspiratory pause and I:E

Respiratory mechanics and gas exchange during one-lung ventilation for thoracic surgery: the effects of end-inspiratory pause and I:E

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-16009696
Enrollment
Unknown
Registered
2016-11-01
Start date
2016-12-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thoracic surgery

Interventions

A:I:E=1:2
TIP:TI=0%, TIP:TI=10% and TIP:TI=20% each for 30 minutes after one lung ventilation
B:I:E=1:1

Sponsors

Shihezi University, Shihezi, the Xinjiang Uygur Autonomous Region
Lead Sponsor

Eligibility

Sex/Gender
All
Age
19 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age 19 to 60 years; the American Society of anesthesiologists (ASA) grade I-II; New York Heart Association (NYHA) cardiac function I-II; 18 < body mass index (BMI)< 28;Surgery time is expected to exceed 2H; the patient has improved the preoperative pulmonary function and heart color Doppler ultrasound examination.

Exclusion criteria

Exclusion criteria: There is a history of liver, kidney and thyroid disease in patients with obstructive and restrictive ventilation dysfunction, and other underlying diseases, such as anemia and circulatory system disease, as well as other experimental results.

Design outcomes

Primary

MeasureTime frame
blood gas analysis;intrapulmonary shunt;—

Countries

China

Contacts

Public ContactDai Zhigang

The First Affiliated Hospital of Shihezi University

379283032@qq.com+86 13677536767

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026