total intravenous anesthesia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Aged 18-65 years old; Elective operation under general anesthesia and 1-3 estimated surgical hours; American Society of Anesthesiologists (ASA) physical status I–II; Body mass index (BMI)18.5-24.9 kg/m^2; informed consent is obtained.
Exclusion criteria
Exclusion criteria: psychiatric and neurological disorders; Impaired cardiac, pulmonary, hepatic and renal functions; sleep apnea hypopnea syndrome; sedative and analgesic drug therapy and abuse; Contraindication for and allergy to any sedative and analgesic drug.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| comparison between Anesthetic depth Index and Bispectral Index (Bland-Altman consistency test); | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlation between the Anesthetic depth Index and the concentration of propofol in effect compartment;the prediction probability (Pk) of Anesthetic depth Index;the Anesthetic depth Index when 50%, 95% people Lost consciousness; | — |
Countries
China
Contacts
Beijing Chaoyang Hospital affiliated to Capital Medical University