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Explore Tai Chi exercise in improving knee osteoarthritis symptoms based on fMRI: a clinical study

Explore Tai Chi exercise in improving knee osteoarthritis symptoms based on fMRI: a clinical study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-16009308
Enrollment
Unknown
Registered
2016-10-03
Start date
2015-08-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

knee osteoarthritis

Interventions

Cycling group:Cycling exercise
Wellness education group:Wellness education

Sponsors

Fujian University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1.Be diagnosed with knee osteoarthritis according to the Diagnostic and Therapeutic Criteria from Committee of the American Rheumatism Association(Arthritis Rheum:1986, 29:1039–1049); 2.Aged 40-70 years,BMI=30kg/m2; 3.Kellgren and Lawrence (K/L) grade 2 or 3; 4.WOMAC pain subscale score (visual analog version) of = 40 (range 0 to 500); 5.The score of Brief Pain Inventory (BPI) >2; 6.The score of Beck Depression Inventory(BDI) <14; 7.Information consent ,participate voluntary.

Exclusion criteria

Exclusion criteria: 1. Participants who have bleeding tendency; 2. Any intra-articular steroid injections in three months or reconstructive surgery within six months; 3. Knee pain due to causes other knee osteoarthritis, such as inflammation; 4. Primary or secondary muscle disease such as idiopathic inflammatory myopathy, progressive muscular dystrophy, glycogen storage disease; 5. Serious knee joint varus or valgus deformity; 6. Psychophtic, without independent capacity and can not cooperate with the clinical observation and treatment; 7. Seriously joint instability and limb alignment offset caused by lower extremity fractures or knee trauma, or uneven of articular surface because of fractures; 8. regular aerobic exercise (3 months with a frequency more than 3 times per week were considered as the minimal standard for regular aerobic exercise); 9. Serious medical conditions that limit his/her ability to safely participate in either the Tai Chi or baduanjin programs, including severe organ failure, severe cardiovascnlar and cerebrovascular diseases, severe musculoskeletal system disease, and other sports contraindications; 10. MRI contraindications (e.g.non-removable denture, cardiac pacemaker) and taking benzodiazepines or other medications that may influence brain imaging; 11. The Mini-Mental Status Examination score < 24.

Design outcomes

Primary

MeasureTime frame
knee pain;WOMAC physical function;

Secondary

MeasureTime frame
cognitive function;blood index;functional magnetic resonance imaging (fMRI);Tea questionnaire;Qualitative research;

Countries

China

Contacts

Public ContactTaojing
taojing01@163.com13305029119

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 20, 2026