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Perioperative esmolol injection and acute kidney injury associated with CPB after cardiac surgery

Perioperative esmolol injection and acute kidney injury associated with CPB after cardiac surgery

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-16009203
Enrollment
Unknown
Registered
2016-09-13
Start date
2016-09-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

heart surgery

Interventions

Treatment group:Esmolol will giving at the begining of anaesthesia by 50ug/kg/min
100ug/kg/min at the transfer the machin, stop at Cardiac Cardiac Resuscitation
Control:0?9% NS

Sponsors

Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. aged 18 yeas and above; 2. Heart surgery; 3. CABG with CPB; 4. Valve surgery with CPB; 5. CABG with other heart surgery 6. valve surgery with other heart surgery 7. agreement to participate.

Exclusion criteria

Exclusion criteria: 1. Emergency heart surgery 2. heart surgery without CPB 3. heart surgery with deep hypothemia 4. Ascending aortic surgery 5. Correction of congenital heart disease 6. allergy to Esmolol 7. Liver and kidney dysfunction 8. Severe dehydration and severe malnutrition or Hb<10g/dl 9. Mental or other reasons 10. Participating in other clinical drug research in the past three months 11. Cardiac shock or placement of IABP.

Design outcomes

Primary

MeasureTime frame
AKI;Rate of mortality;—

Countries

China

Contacts

Public ContactAijun XU

Department of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology

ajxu@tjh.tjmu.edu.cn+86 027 83665431

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026