chronic obstructive pulmonary disease
Conditions
Interventions
The experimental group ?:Conventional therapy +inhalation of budesonide
The experimental group ?:Conventional therapy +inhalation of budesonide andterbutaline
Sponsors
Qilu Hospital of Shandong University
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Male or female aged 40-75 years old; 2. Patients with COPD; 3. At the first day of remission of acute exacerbation symptoms in patients with COPD; 4. Signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Any other respiratory diseases are diagnosed:asthma, interstitial pneumonia, pulmonary tuberculosis, community-acquired pneumonia, bronchiectasis, lung cancer, pulmonary embolism, etc; other system diseases: coronary heart disease, myocarditis, heart failure, neuromuscular disease, decompensated liver cirrhosis, etc.; 2. Blood ALT or AST exceeded the upper limit of 2 times the normal value and blood Cr exceeded the upper limit of 1.5 times the normal value; 3. Left ventricular dysfunction, or nausea; 4. Positive HIV; 5. Acute cerebrovascular event (stroke, transient ischemic attack, acute coronary syndrome) in past 3 months; 6. Pregnant or planning a pregnancy or pregnancy; 7. Underwent pneumonectomy surgery or other lung function may affect the test results of all the operation in the past 12 months; 8. Not a cure for cancer; 9. Drinking, drug addiction, with a history of mental illness, no cooperation with the relevant examination of the project due to mental problems or other reasons; 10. In other drug clinical trials, or less than 3 months of the cessation time; 11. Not suitable for follow-up subjects; 12. Not signing the informed consent form; 13. Researchers believe that other reasons are not suitable for clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The characteristics of lung function in recovery stage of AECOPD.;The frequency ofemergency or hospitalization due to acute exacerbation of COPD.; | — |
Countries
China
Contacts
Public ContactLiang Dong
Qilu Hospital of Shandong University
Outcome results
None listed