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Effect of creatine phosphate sodium on BIS and recovery quality during the general anesthesia emergence period in elderly patients

To observe the effect of creatine phosphate sodium on BIS and recovery quality during the general anesthesia emergence period in elderly patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-16009169
Enrollment
Unknown
Registered
2016-09-07
Start date
2016-11-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Elderly patients undergoing transabdominal cholecystectomy

Interventions

P:Patients were intravenously infused with 1.0g creatine phosphate sodium melted in 100 ml normal saline in thirty minutes at the same time of surgical incision
C:Patients were intravenously infused with 100 ml normal saline in thirty minutes at the same time of surgical incision

Sponsors

Department of Anesthesiology, Nanjing Jiangning Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 80 Years

Inclusion criteria

Inclusion criteria: One hundred and twenty ASA I or II patients aged 65-80 yr undergoing transabdominal cholecystectomy by general anesthesia randomly allocated into two groups(n=60 each)group creatine phosphate (P) and group control(C) according to random numbers generated by computer. Preoperative patients have normal liver and kidney function, no cardiovascular system, respiratory disease, no mental and neurological diseases, no long-term opioid or diazepam drug history.

Exclusion criteria

Exclusion criteria: Surgical time was shorter than 30min, longer than 2h, and patients with more than 400mL bleeding during surgery were excluded from this study.

Design outcomes

Primary

MeasureTime frame
BIS;

Countries

China

Contacts

Public ContactWang Wei

Department of Anesthesiology, Nanjing Jiangning Hospital

278614725@qq.com+86 13851885625

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026