refractory gastroesophageal reflux disease
Conditions
Interventions
experimental group:take the Traditional Chinese medicine granule after mixing it with water, 150ml, bid
experimental group:acupoint thread-embedding
control group:oral Pantoprazole Sodium Enteric-coated Capsules, 40mg, bid
Sponsors
China academy of Chinese Medical Sciences Wangjing hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. In accordance with the diagnostic criteria of the disease; 2. Aged 18-70 years, male and female; 3. Participants know the situation and voluntarily signed the informed consent; 4. Live in the local, be able to do treatment follow-up, own certain reading ability.
Exclusion criteria
Exclusion criteria: 1. Women in pregnancy and lactation; 2. People who have connective tissue disease, diabetes and other endocrine and metabolic diseases,menopausal syndrome,severe primary heart, liver, lung, kidney, blood, or severe disease affecting their survival; 3. Disabled patients (blind, deaf, mute, mental retardation, physical disability) prescribed by law; 4. Suspect or do have a history of alcohol, drug abuse; 5. Other lesions that have reduced the likelihood of entering a group or the complexity of the research; 6. Allergies, such as those with two or more of the drug or food allergies, or those who are allergic to this drug; 7. Patients participating in clinical trials of other drugs; 8. In the severe anxiety and depression, suicidal patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reflux symptom score;Inflammation score under endoscopy;PH value of esophagus in 24 hours; | — |
Secondary
| Measure | Time frame |
|---|---|
| TCM symptom score;Survey on the quality of life related with health;Self rating Anxiety Scale;Self rating Depression Scale; | — |
Countries
China
Contacts
Public ContactWei Wei
China academy of Chinese Medical Sciences Wangjing hospital
Outcome results
None listed