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Effect of creatine phosphatesodium pretreatment in obstructive jaundice patients on cardiac inhibition caused by propofol

Effect of creatine phosphatesodium pretreatment for obstructive jaundice patients on cardiac inhibition caused by propofol

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-16008980
Enrollment
Unknown
Registered
2016-08-05
Start date
2016-08-12
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obstructive jaundice

Interventions

experimental group:propofol routine+phosphatesodium pretreatment
control group:propofol routine

Sponsors

Eastern Hepatobiliary Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: patients with obstructive jaundice caused by periampullary malignant tumor or hilar cholangiocarcinoma and TBL greater than 50umol/L, ASA I-III.

Exclusion criteria

Exclusion criteria: 1. patients with hypertension, coronary heart disease, arrhythmia, acute and chronic heart failure and so on that affects the heart function; 2. patients with severe liver, lung and renal disfunction; 3. bleeding during operation is greater than 1200ml; 4. the level of BMI is greater than 28 or less than 18; 5. patients paticipating other clinical trail or with other reasons not suitable for clinical trials according to the reseachers.

Design outcomes

Primary

MeasureTime frame
heart rate;blood pressure;Central venous pressure;APCO;CO/CI;SV/SVI;SVR/SVRI;SVV;—

Countries

China

Contacts

Public ContactZhijie Lu

Department of Anesthesiology, Eastern Hepatobiliary Hospital, Second Military Medical University

lzjwxyz@163.com+86 13501621611

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026