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Repeat trabeculectomy versus Ahmed glaucoma valve implanation of primary open angle glaucoma with failed initial trabeculectomy

Repeat trabeculectomy versus Ahmed glaucoma valve implanation of primary open angle glaucoma with failed initial trabeculectomy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-16008954
Enrollment
Unknown
Registered
2016-08-02
Start date
2016-09-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

primary open angle glaucoma

Interventions

experimental group:complex trabeculectomy
control group:Ahmed glaucoma valve implantation

Sponsors

Mingkai Lin
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. The patient aged 18 to 70 years old, diagnosed as POAG and had the history of trabeculectomy; 2. It is fail to form successful bleb after the 1st trabeculectomy, and the IOP was =18mmHg after maximal ocular hypotensive agents; 3. Anterior chamber angle is open by gonioscope; 4. There are progressive visual field defect and/or missing retinal ganglion ceils and axon; 5. Voluntarily signed informed consent; 6. No surgery and anesthesia contraindications.

Exclusion criteria

Exclusion criteria: 1. Reject study and follow visit; 2. Have accepted needling revision surgery and achieved target IOP; 3. Filtering bleb is leaking, had or had the risk of bleb related entophthalmia; 4. High myopia or no light perception; 5. Have Conjunctival scarring because of trauma or infection,except for trabeculectomy; 6. Have uncontrollable infection in the ocular surface; 7. heart liver and kidney functions damage; severe gastrointestinal disease; mental abnormalities; diabetic; 8. Have contraindication of glucocorticoid in the ocular surface; 9. Had the history or the plan of intraocular operation except trabeculectomy; 10. Had secondary factors, such as neovascular glaucoma or uveitis glaucoma; 11. Cannot tolerate surgery or anesthesia.

Design outcomes

Primary

MeasureTime frame
Success rate of surgery;

Countries

China

Contacts

Public ContactMingkai Lin

Zhongshan Ophthalmic Center, Sun Yat-sen University

linmk@mail.sysu.edu.cn+86 13928848818

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026