infertility
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Premenopausal females, aged 37 to 44 years; (2) Have given birth to a health baby; (3) Bilateral ovaries; (4) AFC=10, and AMH=2.0 ng/ml.
Exclusion criteria
Exclusion criteria: (1) Endometriosis disease; (2) Intrauterine adhesions history; intrauterine membrane polyp, tuberculosis and inflammation; (3) Uterine malformation, multiple uterine myoma, uterine intramural myoma >3cm, submucous myoma; (4) Unprocessed hydrosalpinx; (5) Adverse reproductive history; greater than or equal to 2 times history of unexplained abortion; (6) Chromosomal abnormalities or other genetic disease; (7) Infertility caused by male factors, such as puncture testicular, SRT did not see the class A and class B sperm; (8) Without high quality embryos in past COH cycles; (9) Patients with poor ovarian response, the standard of poor ovarian response accords with Bolognacriteria standard, that is at least meet 2 among the following 3: 1) Elder years (=40 years) or have other known inherited or acquired risk factors that may reduce follicle; 2) History of cancellation of the cycles because of less than 3 follicular development, or history of egg number less than 4 after at least using FSH150IU once a day; 3) Ovarian reserve function test abnormalities, including sinus follicle number less than 5-7 (AFC) or AMH less than 0.5 to 1.1 ng/ml.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| live birth rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| cancellation rate;pregnancy rate;miscarriage rate; | — |
Countries
China
Contacts
Reproductive & Genetic Hospital of CITIC-XIANGYA, Changsha, Hunan