nonalcoholic fatty liver disease
Conditions
Interventions
Test group:lifestyle interventions
control group:no lifestyle intervention
Sponsors
Huadong Hospital
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: Between January 2012 and June 2012, 319 male patients with NAFLD referred to the outpatient department of gastroenterology, Huadong Hospital, Fudan University. Those permanently living in Shanghai and = 45 years old, male patients, and confirmed by liver ultrasonography to have different extent of liver fatty change were screened for eligibility.
Exclusion criteria
Exclusion criteria: Exclusion criteria included: (1) a history of alcohol intake greater than 20 g/day or 140 g/week; (2) evidence of viral hepatitis, drug-induced liver disease, autoimmune liver disease, total parenteral nutrition, genetic disorders such as Wilsons disease, alpha-1-antitrypsin deficiency, etc., which could lead to liver steatosis; (3) consumption of hypoglycemic, hypolipidemic, anti-inflammatory and weight loss agents as well as any drug known to influence liver function, and the presence of coronary, renal, pulmonary and thyroid diseases; (4) patients whose transaminase is more than double upper limit of the normal reference value.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ALT;TCH;LDL;HDL;TG; | — |
Countries
China
Contacts
Public ContactYiqin Huang
Huadong Hospital
Outcome results
None listed