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Effectiveness of Procalcitonin-Guided Antibiotic Therapy in Acute Exacerbations of Bronchiectasis: a Randomized Controlled Trial

Effectiveness of Procalcitonin-Guided Antibiotic Therapy in Acute Exacerbations of Bronchiectasis: a Randomized Controlled Trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-16008910
Enrollment
Unknown
Registered
2016-07-26
Start date
2016-08-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bronchiectasis

Interventions

Procalcitonin group :according to procalcitonin guidance of antibiotic therapy group

Sponsors

Laiwu City People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Bronchiectasis was diagnosed by high-resolution computed tomography based on the criteria published by McShane PJ et al. 2. Acute exacerbations of bronchiectasis; 3. Aged >= 18 years; 4. Procalcitonin been detected after admission.

Exclusion criteria

Exclusion criteria: 1. Associated with chronic obstructive pulmonary disease; 2. Associated with asthma; 3. Traction bronchiectasis caused by pulmonary fibrosis; 4. Rule out other possible cause procalcitonin increased diseases such as cancer, connective tissue disease, active tuberculosis, chronic liver disease and respiratory system than the bacterial infection; 5. Clinical data were incomplete; 6. Can not follow up with the person.

Design outcomes

Primary

MeasureTime frame
Clinical effectiveness rate;

Countries

China

Contacts

Public ContactZhou Yufa

Laiwu City People's Hospital

qiqianqlh@126.com+86 13963457090

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026